A study being published in next month’s issue of the Journal of Neurology, Neurosurgery & Psychiatry, and published online early by the National Institute of health, has found that THC (delta-9-tetrahydrocannabinol) can treat Parkinson’s disease.
According to the study’s introduction; “Cannabinoids such as Δ9-tetrahydrocannabinol (Δ9-THC) are neuroprotective in animal and cell culture models of Parkinson’s disease (PD). In a PD cell culture model we recently demonstrated that Δ9-THC is neuroprotective through activation of the nuclear receptor peroxisomal proliferator-activated receptor γ (PPARγ)”.
Researchers, while studying the effects of THC on these cell-culture models of Parkinson’s disease, found that; “Δ9-THC resulted in significant inhibition of MPP+ induced oxidative stress”. They conclude that; “Δ9-THC induces PPARγ dependent mitochondrial biogenesis, a mechanism that may be beneficial for the treatment of PD.”
The study was conducted by researchers at the Plymouth University Peninsula Schools of Medicine and Dentistry.